enzymy, k.lipoová

Anonym Zezamyn22.09.2018 20:06 Nahlásit
jaký enzym využívá jako kofaktor k. lipoovou? Může být třeba dihydrolipoyltransacetyláza?? a jak by konkrétně vypadala reakce? Děkuji!

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Anonym Gadikip22.09.2018 22:45 Nahlásit
Lipoic acid is cofactor for at least five enzyme systems. Two of these are in the citric acid cycle through which many organisms turn nutrients into energy. Lipoylated enzymes have lipoic acid attached to them covalently. The lipoyl group transfers acyl groups in 2-oxoacid dehydrogenase complexes, and methylamine group in the glycine cleavage complex or glycine dehydrogenase.

2-Oxoacid dehydrogenase transfer reactions occur by a similar mechanism in:

the pyruvate dehydrogenase complex
the α-ketoglutarate dehydrogenase or 2-oxoglutarate dehydrogenase complex
the branched-chain oxoacid dehydrogenase (BCDH) complex
the acetoin dehydrogenase complex.

viac nájdeš tu:

https://en.wikipedia.org/wiki/Lipoic_acid
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